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- Time of issue:2020-03-19 00:00:00
Hunan Xenolife Biotechnology Co., Ltd
Hunan Xenolife Biotechnology Co., Ltd. is mainly engaged in the research and development and preparation of xenotransplantation products. The company has a high-level R & D team. In the field of xenotransplantation, he has carried out close cooperation research with the Institute of cell transplantation and gene therapy of Central South University (Central South University holds the state-owned equity part of the company).
At present, the company covers an area of 50 mu in Xiangjiang new area of Changsha National High tech Zone. In August 2012, the company established a production base of medical grade (DPF) donor pigs that meets the World Health Organization standards and has independent intellectual property rights. At the same time, it established a cGMP standard cell preparation center, which has initially covered the breeding, breeding, donor cell preparation, standard formulation and management, and transplantation of medical grade donor pigs a complete industrial chain of technology preclinical research, clinical application and development. At present, the company has its own brand of donor pig inbred line for islet cell transplantation - "xeno-1" (the pig that meets the DPF Standard Test), and on this basis, it has developed a human-oriented gene modified pig "xeno-2" for islet cell transplantation.
The company has part of intellectual property rights of the complete set of technology system for the treatment of type 1 diabetes by transplanting pig pancreatic island cells through hepatic artery and portal vein. At present, the company has been authorized 7 national invention patents related to xenotransplantation and cell therapy. At the same time, the company cooperated with Xiangya third hospital to successfully complete the small sample clinical research on the treatment of type 1 diabetes mellitus by pig islet transplantation. The comprehensive efficacy index of the initial cases has reached a high level in the same period in the world, and will gradually enter the industrialization development track in the future.
The company hired International Xenotransplantation scientists (including American, Australian xenotransplantation scientists and the president of International Xenotransplantation Association) as its scientific consultants, which greatly improved the company's R & D strength. The project of "DPF donor cultivation and research and development and industrialization of xenotransplantation of islets of Langerhans" cooperated by the company and Central South University was approved as a major science and technology project of Hunan Province in 2014, in addition, the project of "key technology and demonstration of biosafety of xenotransplantation" reached a high level, and won the first prize of 2015 Hunan Technology Invention Award.
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